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by induction of mitogen-activated protein kinase phosphatase-1 (MKP-1) via PKCα
thereby inhibiting tumor cell proliferation
Ceranib-2 is a potent and nonlipid ceramidase inhibitor that inhibits cellular ceramidase activity with an IC50 of 28 μM in SKOV3 cells
Houghton PJ
TC 1 12124 by induction of mitogen-activated proteinProduct information CAS Number: 362512 81 0 Molecular Weight: 297. 37 Formula: C19H20FNO Chemical Name: 5 [2 (3 fluorophenyl)ethyl] 5 azahexacyclo[5. 4. 1. 0,. 0,. 0,. 0,]dodecan 4 ol Smiles: OC12C3C4C(C5C6CC(C15)C3C46)N2CCC1C=CC=C(F)C=1 InChiKey: FYGREZKTJIXWIH UHFFFAOYSA N InChi: InChI=1S C19H20FNO c20 9 3 1 2 8(6 9)4 5 21 18 14 10 7 11 13 12(10)15(18)17(13)19(21,22)16(11)14 h1 3,6,10 18,22H,4 5,7H2 Technical Data Appearance: Solid Power Purity: 98%
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