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Miglustat is used to treat adults with mild-to-moderate Type I Gaucher disease and it is the first treatment to be approved for patients with Niemann–Pick type C disease
a novel intracellular Ca2+ handling modulator that acts through reverse-mode Na+/Ca2+ exchanger inhibition and potential sarcoplasmic reticulum (SR) Ca2+ uptake enhancement
an N-demethylated metabolite of Verapamil
CGP 35348 is a selective antagonist of γ-aminobutyric acidB (GABAB) receptor with IC50 value of 34 μM
PF-06700841 an) Miglustat is used to treatPF 06700841 is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. PF 06700841 also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6. 49 M, respectively. Product information CAS Number: 1883299 62 4 Molecular Weight: 389. 40 Formula: C18H21F2N7O Chemical Name: 4 [(1R,5S) 8 [(1S) 2,2 difluorocyclopropanecarbonyl] 3,8 diazabicyclo[3. 2. 1]octan 3 yl] N (1 methyl 1H pyrazol 4 yl)pyrimidin 2 amine Smiles:
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